During my stay at the European Bioinformatics Institute (EBI), I had the opportunity to learn from the knowledgeable team and explore their suggestions. I had the chance to understand much more concerning the EBI and especially the European Genome-Phenome Archive (EGA). I will also be able to pursue a search on SMPC now that I had the chance to explore at the EBI. The next step would be to try working on a gene and search for genome-wide possibilities.
Read MoreTo help researchers learn about finding, accessing and analysing sensitive human data in a federated fashion, the CINECA project has developed a learning pathway. In this blog, we describe why federated data analysis is important, what is included in the learning pathway and how it can be accessed.
Read MoreIn the Passport is the glue between the researcher, data and computing blog post I introduced GA4GH Passports as an enabler of “the bring compute to data” paradigm. CINECA WP2 also contributed to GA4GH Passport standard for Digital identity and access permissions publication in Cell Genomics in autumn 2021.
Read MoreThe EUCAN Cluster consists of seven projects (CINECA, EUCANCan, EUCAN-Connect, euCanSHare, iReceptor Plus, and ReCoDID) that received funding under the same Horizon 2020 call, SC1-BHC-05-2018.
This document provides a high-level overview of each project in the cluster.
Read MoreIn collaboration with other GA4GH-associated projects, CINECA is developing infrastructure which will permit effective use of widely-dispersed data increasing the size and quality of datasets available for disease research. In alignment with community standards, using standardised interfaces, data analysis will be federated and migrated to the data, respecting data access restrictions.
Solutions CINECA is adopting from the Discovery Work Stream include the Data Connect and Beacon v2 API, while from the DURI and Data Security Work Streams the GA4GH Passports, AAI and DUO are being utilised.
Recently WP4 has delivered a simple demonstrator pipeline to perform a federated joint variant genotyping analysis. The goal of this use case is to demonstrate how a simple metric (in this case, allele frequency) can be computed in a federated manner, without requiring ever collecting the individual level data in a central location.
Read MoreThis month’s blog was written by Nicola Mulder, Professor and head of the Computational Biology division at the University of Cape Town, and Principal investigator of H3ABioNet, a Pan African bioinformatics network for H3Africa, and Mamana Mbiyavanga, a Bioinformatics Scientist and PhD student at UCT, who contribute to a diverse range of CINECA work packages. This blog is less of a technical report in our Global Alliance for Genomics and Health (GA4GH) standards series than the previous 4, and more of a report on how WP6 - ‘Outreach, training and dissemination’ is contributing to developing better implementation of GA4GH standards.
Read MoreThis month’s blog was written by Melanie Courtot, metadata standards coordinator at EMBL-EBI and co-Work Package Lead of CINECA WP3 - Cohort Level Metadata Representation. This blog is the fourth in our Global Alliance for Genomics and Health (GA4GH) standards series, presenting an overview of how GA4GH standards are being developed and implemented by CINECA. In our April post about Passport, Mikael from CINECA WP2 explained the importance of controlled-access to protect sensitive data, federated data access in the cloud and how Passport enables researchers to authenticate - prove they are who they say they are.
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